Error ..... opening applications

with opening applications. displays a white background without the link of company

Have you ever created a company in Manager? Or is this the first time you have used Manager?

I have created 2 companies in manager and i was using it for over six months.It appears an empty window without options

I had a similar experience about a year ago. I use a Mac. Other users have reported similar things, but as far as I know, @lubos could never replicate the problem. In my case, it was fixed by downloading and reinstalling. Have you tried that?

i have tried that but i have the same problem

Try to install server edition using tutorials here: http://www.manager.io/server/tutorials

Then see if you can access Manager that way.