From post Installation Problem (Not open when i installed)
These two topics sound identical and it would appear that a windows update is the problem. This sounds most likely as a number of people have reported random issues with Windows 10 and Manager lately. I suspect that Windows Update may be the root cause of all of them - although this does not negate earlier post about how manager installs the software per user instead of per computer.
To the OP have you tried uninstalling this KB to see if this fixes the issue - in which case Lubos can fix Manager to work with that update.