Most of my employees are paid on commission

Most of my employees are paid on commission. Is there a way to set this up in the employee management and enter the %?

No, you need to enter the amount. So you may have to use a spreadsheet to get the amount for each employee based on their proportion of the commission.

I don’t understand how to calculate the commission

Presumably you have Written agreement with your employees which details how the commission is calculated

Manager is an accounting system and does not have any features to calculate commission automatically

Please be more detailed about what you are asking¹

The employee receives a commission based on the profit achieved from selling the service
If the service was purchased for $100 and sold for $150
So 150 is deducted from 100 and the profit appears as only $50
The employee gets a percentage of this $50 only
How is this situation coordinated in the manager

You do the sums externally and copy the total to a line item in each employee’s pay sheet within Manager.

Depending on how you enter data into Manger and the details of the pay agreement, a Manager report may help you get the data to calculate the required total.