These are not errors. Even at 15 decimal place accuracy, the conversions will not be exact. Transactions can only be posted at the smallest division of a currency, so positive and negative differences will add up over hundreds of transactions. This is simply the nature of multi-currency operations.
If the 4.35 is in INR, yes, you might consider the amount negligible. But it should only be there if you rounded on some sales invoice. The rounding expenses did not come from exchange rate differences or forex gains/losses. You need to track down where you introduced rounding in a sales invoice. An easy way to look is to begin a Batch Update for sales invoices and look at the column in the spreadsheet indicating rounding to discover which invoice(s) are involved. (Then abandon the update.)